期刊
LANCET
卷 365, 期 9477, 页码 2122-2124出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(05)66735-9
关键词
-
资金
- NCI NIH HHS [CA-82481] Funding Source: Medline
- NHLBI NIH HHS [HL-63766, F32-HL-71407] Funding Source: Medline
Tissue engineering has made considerable progress in the past decade, but advances have stopped short of clinical application for most tissues. We postulated that an obstacle in engineering human tissues is the limited replicative capacity of adult somatic cells. To test this hypothesis, the effectiveness of telomerase expression to extend cellular lifespan was assessed in a model of human vascular tissue engineering. Telomerase expression in vascular cells isolated from elderly patients enabled the successful culture of engineered autologous blood vessels. Engineered vessels may one day provide a source of bypass conduit for patients with atherosclerotic disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据