4.7 Review

Dendrimeric micelles for controlled drug release and targeted delivery

期刊

MOLECULAR PHARMACEUTICS
卷 2, 期 4, 页码 264-272

出版社

AMER CHEMICAL SOC
DOI: 10.1021/mp050020d

关键词

micelle; drug delivery; dendrimers; controlled release; targeted delivery; polymer-drug conjugates

资金

  1. National Institutes of Health

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This review highlights the developments in dendrimer-based micelles for drug delivery. Dendrimers, the perfectly branched monodisperse macromolecules, have certain structural advantages that make them attractive candidates as drug carriers for controlled release or targeted delivery. As polymeric micelle-based approaches precede the work in dendrimers, these are also discussed briefly. The review concludes with a perspective on possible applications of biaryl-based dendrimeric micelles that exhibit environment-dependent conformations, in drug delivery.

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