期刊
FEMS MICROBIOLOGY LETTERS
卷 248, 期 1, 页码 37-45出版社
OXFORD UNIV PRESS
DOI: 10.1016/j.femsle.2005.05.019
关键词
2-methacryloyloxyethyl phosphorylcholine; superhydrophilicity; hydrophobic; microbial retention
类别
The present study compares the retention of four species that are often isolated in association with biomedical device-related infections - Staphlylococcus aureus, Streptococcus mutans, Pseudomonas aeruginosa, and Candida albicans - to three different surfaces. All four bacterial species were found to bind significantly less well to MPC-coated surfaces than to non-coated surfaces. We attribute this effect to the superhydrophilicity of MPC-coated surfaces, whereas hydrophobic surfaces are well known to reduce bacterial retention and thus to inhibit a crucial step in the formation of bacterial biofilms that lead to biomedical device-related infections and complications. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
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