期刊
APPLIED BIOCHEMISTRY AND MICROBIOLOGY
卷 47, 期 6, 页码 635-639出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0003683811060056
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资金
- FTsP Research and Scientific-Pedagogical Personnel of Innovational Russia, [14.740.11.0382]
New hydrophilic polymer sorbents comprising reactionary sites which are complementary to a molecule of antibiotic erythromycin were synthesized by the method of molecular imprinting. A series of similar sorbents without reactionary sites was used for comparison of sorption characteristics. Sorption of erythromycin on both types of polymer sorbents synthesized was studied in a wide range of pH and ionic strength. Selectivity of erythromycin sorption on molecularly imprinted cross-linked polymers was shown to depend on the specific interaction of target molecule with polymer matrix. This type of sorbent is perspective for the development of antibiotic purification directly from a culture medium Saccharopolyspora erythreus. DOI: 10.1134/S0003683811060056
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