4.7 Article

Inventory of the proteins in Neisseria meningitidis serogroup B strain MC58

期刊

JOURNAL OF PROTEOME RESEARCH
卷 4, 期 4, 页码 1361-1370

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AMER CHEMICAL SOC
DOI: 10.1021/pr0500511

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Neisseria meningitidis; functional genomics; proteome; MALDI-TOF; two-dimensional electrophoresis; 2D-minigel; peptide mass fingerprint

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A protein inventory of Neisseria meningitidis strain MC58, a meningococcal strain belonging to the serogroup B, was performed by proteomics. A differential extraction procedure was employed and 238 protein species were identified by 2D mini-maps and MALDI-ToF analyses. In this catalog, we detected protein products from 33 genes, which were not yet annotated in previous N. meningitidis proteomic studies. This approach is suitable for high-throughput studies on differential expression of N. meningitidis genomes.

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