期刊
PEDIATRIC SURGERY INTERNATIONAL
卷 21, 期 7, 页码 578-581出版社
SPRINGER
DOI: 10.1007/s00383-005-1451-4
关键词
caudal regression syndrome; caudal dysplasia sequence; sacral agenesis; congenital malformations
Caudal regression syndrome is a rare disorder of distal spinal segments affecting the development of the spinal cord, with attendant sequelae. Intelligence is preserved. The exact etiology is elusive, though maternal diabetes, genetic factors, and hypoperfusion might play roles. Recently, the role of teratogens has been studied in animal models. Treatment is difficult, multidisciplinary, and largely supportive. Lower limb deformities with sensory and motor loss and neurogenic bladder call for intensive and long-term attention.
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