期刊
JOURNAL OF NEUROIMMUNOLOGY
卷 164, 期 1-2, 页码 161-165出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jneuroim.2005.04.001
关键词
P/Q-type calcium channel antibody; Lambert-Eaton myasthenic syndrome; paraneoplastic cerebellar degeneration; small cell lung carcinoma; survival
To assess the survival impact of the presence of P/Q-type calcium channel antibodies in patients with small cell lung carcinoma (SCLC), we examined the frequency of the antibodies and Lambert-Eaton myasthenic syndrome (LEMS) in 148 consecutive patients with SCLC, and in 30 patients with paraneoplastic cerebellar degeneration and SCLC, and studied their relation with survival. In both series, only patients with LEMS had a remarkably long survival, whereas presence of the antibodies without LEMS did not result in a better prognosis. (C) 2005 Elsevier B.V. All rights reserved.
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