期刊
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
卷 136B, 期 1, 页码 72-74出版社
WILEY-BLACKWELL
DOI: 10.1002/ajmg.b.30196
关键词
Parkinson's disease; genetics; apolipoprotein E
Analysis of the apolipoprotein E genotype in sibpairs with Parkinson's disease showed the E4 allele was over represented in those who shared the adjacent chromosome 19 markers. This suggests that apolipoprotein E4 is responsible for the linkage peak in this region and that it is a modest risk factor for Parkinson's disease. (c) 2005 Wiley-Liss, Inc.
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