Inter- and intramolecular radical couplings of ene-ynes or halo-alkenes promoted by an InCl3/MeONa/Ph2SiH2 system

An effective generation of indium hydride (HInCl2) under nonacidic conditions is achieved by transmetalation between Ph2SiH2 and InCl2OMe. The presented system achieves the titled coupling reactions in a radical manner. In particular, the nonacidic character enables the applications to acid-sensitive inter- and intramolecular ene-yne couplings.