Epileptiform EEG abnormalities in children with language regression

The authors examined the records of 149 children with language regression (LR) who had overnight EEG monitoring. Children with isolated LR had a higher frequency of epileptiform abnormalities (60%) than those with LR in the context of autistic regression (31%, p = 0.002) and also a higher rate of clinical seizures (33% vs 8%, p = 0.001). EEG abnormalities in the LR only group were also more prominent. This suggests two subtypes of language regression.