The wettability modification of bio-grade stainless steel in contact with simulated physiological liquids by the means of laser irradiation

Early surface events that occur rapidly upon implantation of a biomaterial into biological fluids determine the subsequent response. These involve wetting by physiological liquids followed by adsorption of proteins and cells to the biomaterials surface. A CO, laser and high power diode laser (HPDL) were used to modify the surface properties of the material and thus manipulate the wettability of the material and its interaction with physiological liquids. The contact angles, theta, of selected test liquids including simulated physiological liquids shows that the wettability of the stainless steel improved after CO2 and HPDL treatment. The determined adhesion work of stainless steel towards stimulated physiological fluid enhanced after laser treatment, implying better interaction with the biological liquids. It is demonstrated that the laser could be a novel and controllable technique for enhancing the biocompatibility of bio-grade stainless steel. (c) 2005 Elsevier B.V. All rights reserved.