期刊
TETRAHEDRON LETTERS
卷 46, 期 30, 页码 5005-5007出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.05.082
关键词
heterocycles; triazoles; amide; tropane; fluorination
The initial synthesis of UK-427,857 (Maraviroc) is described including the preparation of 4,4-difluorocyclohexanoic acid and amide coupling utilizing a polymer supported reagent. (c) 2005 Elsevier Ltd. All rights reserved.
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