期刊
SCIENCE
卷 309, 期 5735, 页码 764-767出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1112699
关键词
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To study adaptation, it is essential to identify multiple adaptive mutations and to characterize their molecular, phenotypic, selective, and ecological consequences. Here we describe a genomic screen for adaptive insertions of transposable elements in Drosophila. Using a pilot application of this screen, we have identified an adaptive transposable element insertion, which truncates a gene and apparently generates a functional protein in the process. The insertion of this transposable element confers increased resistance to an organophosphate pesticide and has spread in D. melanogaster recently.
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