期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 78, 期 21, 页码 7801-7804出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02023-12
关键词
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资金
- CEU [PITN-GA-2008-215524, 244093]
- transnational SysMO project BACELL SysMO 1 through the Research Council for Earth and Life Sciences of the Netherlands Organization for Scientific Research
- transnational SysMO project BACELL SysMO 2 through the Research Council for Earth and Life Sciences of the Netherlands Organization for Scientific Research
Bacterial twin-arginine translocases can export fully folded proteins from the cytoplasm. Such proteins are usually resistant to proteolysis. Here we show that multiple extracellular proteases degrade the B. subtilis Tat substrate YwbN. This suggests either that secreted YwbN is not fully folded or that folded YwbN exposes protease cleavage sites.
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