期刊
JOURNAL OF MOLECULAR EVOLUTION
卷 61, 期 2, 页码 253-263出版社
SPRINGER
DOI: 10.1007/s00239-004-0307-1
关键词
continuous evolution; in vitro evolution; isothermal amplification; ligase; mutation; ribozyme; selection
Experimental evolution methods can be used to address and illuminate issues central to the understanding of evolutionary theory. One of the most powerful of-these methods involves the in vitro evolution of nucleic acid enzymes, taking advantage of the direct relationship between the genotype of a nucleic acid sequence and the phenotype of its associated catalytic function. This review and commentary focuses on the past, present, and future potential of systems for the continuous in vitro evolution of nucleic acid enzymes as tools for modeling evolutionary processes in biology. It offers a candid appraisal of both the strengths and the limitations of these systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据