期刊
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
卷 60, 期 8, 页码 904-908出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/znb-2005-0815
关键词
Pseudoceratina purpurea; purpuroceratic acids A and B; aplysamine-2; bromotyrosine derivatives
A collection of the marine sponge Pseudoceratina purpurea from the Gulf of Thailand furnished aplysamine-2, two new bromotyrosine derivatives purpuroceratic acids A and B, two known bromotyrosine derivatives, 3-maleimide-5-oxime and common sponge constituents. Aplysamine-2, purpuroceratic acid A and 3-maleimide oxime were evaluated for their in vitro anticancer activity against three cancer cell lines, but only aplysamine-2 exhibited moderate dose dependent growth inhibitory effects.
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