Bi(OTf)3 and SiO2-Bi(OTf)3 as effective catalysts for the Ferrier rearrangement

Bi(OTf)(3) and SiO2-Bi(OTf)(3) are found to effectively catalyze the Ferrier rearrangement of tri-O-acetyl glycals with different alcohols providing an effective route to 2,3-unsaturated O-glycosides with good anomeric selectivity and good to excellent yields after short reaction times.