期刊
MOLECULAR GENETICS AND METABOLISM
卷 85, 期 4, 页码 323-327出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ymgme.2005.04.011
关键词
SLC2A10; GLUT10; type 2 diabetes; single nucleotide polymorphism; association analysis; Finnish; 20q
资金
- NHGRI NIH HHS [HG00376] Funding Source: Medline
- NIDDK NIH HHS [DK29867, DK62370, R01 DK029867, DK27619] Funding Source: Medline
The SLC2A10 gene encodes a glucose transporter and is located on chromosome 20q13, where evidence has been found for linkage to type 2 diabetes (T2D) in multiple studies. We investigated SLC2A10 as a T2D candidate gene in Finns. We did not confirm the previously reported association between Ala206Thr and fasting insulin and we observed no statistically significant evidence for T2D association with any single marker. We tested haplotypes for association with diabetes-related traits and observed no excess of significant results. Published by Elsevier Inc.
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