期刊
ENDOCRINE
卷 27, 期 3, 页码 307-309出版社
SPRINGER
DOI: 10.1385/ENDO:27:3:307
关键词
adiponectin; PPAR gamma 2
The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) gene and adiponectin, a protein secreted from adipose tissue, have been associated with insulin sensitivity. The present study demonstrates that in Finnish servicemen who were on a high-caloric diet for 6 mo only subjects with the Ala 12 allele of PPAR gamma 2 had a significant increase in adiponectin levels with weight loss induced by heavy exercise. This study demonstrates an interaction of genetic and environmental factors in the regulation of serum adiponectin concentrations.
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