期刊
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
卷 180, 期 8, 页码 1849-1862出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/104265090889512
关键词
condensation; cyclisation using sodium diselenide; dehydroxychlorination; esterification; hydrolysis; Vilsmeier-Haack Reaction
The compounds selenolo(2,3-b)quinoline-2-carboxylic ethyl esters were synthesized in good yields by the reaction of 3-(2-chloro-3-quinolyl)actylic ethyl esters, with the nucleophilic reagent sodium diselenide in ethanol medium under a nitrogen atmosphere. Cytogenetic studies on human blood leucocytes in vitro were evaluated for some of the synthesized compounds. Most of the synthesized compounds were tested for their antibacterial and antifungal activities.
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