Glycosidase inhibition by 1-glycosyl-4-phenyl triazoles

1-Glycosyl-4-phenyl triazoles have been prepared via a copper-mediated [3 + 2] cycloaddition of glycosyl azides with phenylacetylene. These triazoles have been evaluated for their ability to inhibit the enzymatic activity of glycosidases. (c) 2005 Elsevier Ltd. All rights reserved.