期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 75, 期 23, 页码 7548-7550出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.01303-09
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资金
- CONACyT [84648, 81639]
- DGAPA [IN210208, IN222308-3]
Cry11Aa and Cyt1Aa of Bacillus thuringiensis are active against mosquitoes and show synergism. Cyt1Aa functions as a membrane receptor inducing Cry11Aa oligomerization. Here we characterized Cry11Aa helix alpha-3 mutants impaired in oligomerization and toxicity against Aedes aegypti, indicating that oligomerization of Cry11Aa is important for toxin action. Cyt1Aa did not recover the insecticidal activity of Cry11Aa mutants.
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