期刊
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
卷 37, 期 4, 页码 261-268出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10863-005-6636-y
关键词
Acanthamoeba castellanii; TOM complex; Tom70
It is suggested that in the course of the TOM complex evolution at least two lineages have appeared: the animal-fungal and green plant ones. The latter involves also the TOM complexes of algae and protozoans. The amoeba Acanthamoeba castellanii is a free-living nonphotosynthetic soil protozoan, whose mitochondria share many bioenergetic properties with mitochondria of plants, animals and fungi. Here, we report that a protein complex, identified electrophysiologically as the A. castellanii TOM complex, contains a homologue of yeast/animal Tom70. Further, molecular weight of the complex (about 500 kDa) also points to A. castellanii evolutionary relation with fungi and animal. Thus, the data indicates that the TOM complex of A. castellanii is not a typical example of the protozoan TOM complex.
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