期刊
TRENDS IN GENETICS
卷 21, 期 8, 页码 424-427出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tig.2005.06.006
关键词
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Biochemists and geneticists, represented by Doug and Bill in classic essays, have long debated the merits of their methods. We revisited this issue using genomic data from the budding yeast, Saccharomyces cerevisiae, and found that genetic interactions outperformed protein interactions in predicting functional relationships between genes. However, when combined, these interaction types yielded superior performance, convincing Doug and Bill to call a truce.
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