期刊
JOURNAL OF ANTIBIOTICS
卷 58, 期 8, 页码 535-538出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/ja.2005.74
关键词
antifungal; antimicrobial; structure elucidation; Sch 725674
A new macrolide Sch725674 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was accomplished based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 8 and 32 mu g/ml, respectively.
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