4.6 Article

PCR detection of type I polyketide synthase genes in myxobacteria

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APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 74, 期 17, 页码 5571-5574

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AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.00224-08

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  1. New Energy and Industrial Technology Development Organization, Japan [P02038]

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The diversity of type I modular polyketide synthase (PKS) was explored by PCR amplification of DNA encoding ketosynthase and acyltransferase domains in myxobacteria. The sequencing of the amplicons revealed that many PKS genes were distantly related to the published sequences. Thus, myxobacteria may be excellent resources for novel and diverse polyketides.

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