期刊
JOURNAL OF MEDICINAL CHEMISTRY
卷 48, 期 16, 页码 5092-5095出版社
AMER CHEMICAL SOC
DOI: 10.1021/jm050358b
关键词
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Tanaproget represents a potential first-in-class nonsteroidal PR agonist for contraception with improved safety and side effect profiles versus currently available steroidal oral contraceptives. Additional SAR, biological activity, and structural information from a tanaproget/hPR-LBD (hPR-LBD human progesterone receptor ligand binding domain) cocrystal structure will also be presented.
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