期刊
BIOINFORMATICS
卷 21, 期 16, 页码 3424-3426出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bti547
关键词
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DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.
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