期刊
BIOINFORMATICS
卷 21, 期 16, 页码 3435-3438出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bti537
关键词
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An easy-to-use, versatile and freely available graphic web server, Foldindex (R) is described: it predicts if a given protein sequence is intrinsically unfolded implementing the algorithm of Uversky and co-workers, which is based on the average residue hydrophobicity and net charge of the sequence. FoldIndex (R) has an error rate comparable to that of more sophisticated fold prediction methods. Sliding windows permit identification of large regions within a protein that possess folding propensities different from those of the whole protein.
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