Pd(OAc)2/DABCO as a highly active catalytic system for the Heck reaction

The combination of Pd(OAc)(2) and DABCO (triethylenediamine) was observed as an efficient catalytic system for the Heck cross-coupling reaction. In the presence of Pd(OAc)(2) and DABCO, a number of ArX (X = I, Br, and Cl) were coupled with olefins efficiently and selectively to afford the corresponding unsymmetric internal olefins in good to excellent yields. Furthermore, the Pd(OAc)(2)/DABCO-catalyzed Heck cross-coupling reaction provided high TONs up to 1,000,000.