Highly diastereoselective Diels-Alder reactions with enantiopure sulfinyl-substituted 1-hydroxymethyldienes

Enantiopure hydroxy-2- and -3-sulfinyldienes undergo highly selective Diels-Alder cycloadditions with various dienophiles controlled by the chiral sulfur atom. The related hydroxy-2-sulfonyldienes display complementary pi-facial selectivity.