期刊
ARCHIVES OF PHARMACAL RESEARCH
卷 28, 期 9, 页码 1027-1030出版社
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/BF02977396
关键词
Rheum undulatum; Polygonaceae; stilbene; anthraquinone; antidiabetic
The antidiabetic-activity-guided fractionation and isolation of the 80% EtOH extracts obtained from cultivated Korean Rhubarb rhizomes (Rheum undulatum, Polygonaceae) led to the isolation and characterization of one stilbene, desoxyrhapontigenin (1) and two anthraquinones, emodin (2) and chrysophanol (3). Their structures were established by chemical and spectroscopic methods. Compounds 1, 2, and 3 inhibited postprandial hyperglycemia by 35.8, 29.5, 42.3%, respectively.
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