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B. Z. Carter et al.
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Christin Tse et al.
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Mark Wade et al.
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V. Labi et al.
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Ales Tichy et al.
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Discovery of an Orally Bioavailable Small Molecule Inhibitor of Prosurvival B-Cell Lymphoma 2 Proteins
Cheol-Min Park et al.
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Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines:: Mcl-1 inactivation
Min H. Kang et al.
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W. Zhang et al.
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Noxa: at the tip of the balance between life and death
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K. E. Tagscherer et al.
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Luis F. Z. Batista et al.
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Jerry M. Adams et al.
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X. Lin et al.
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Yoshihisa Kubota et al.
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Victoria Del Gaizo Moore et al.
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An accelerated senescence response to radiation in wild-type p53 glioblastoma multiforme cells
Quincy A. Quick et al.
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Life in the balance: how BH3-only proteins induce apoptosis
SN Willis et al.
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V Chaturvedi et al.
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T Oltersdorf et al.
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T Choudhuri et al.
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Gene expression profiling and genetic markers in glioblastoma survival
JN Rich et al.
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Susceptibility of myelomonocytic leukemia U937 cells to the induction of apoptosis by the non-peptidic Bcl-2 ligand HA14-1 is cell cycle phase-dependent
JJ Reiners et al.
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D Nijhawan et al.
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J Lin et al.
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p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation
HA Giebler et al.
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