期刊
CHEMICAL & PHARMACEUTICAL BULLETIN
卷 53, 期 9, 页码 1159-1163出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.53.1159
关键词
plastoquinone; antioxidative activity; lipid peroxidation; radical scavenger; cytotoxic activity; Sargassum micracanthum
Four new plastoquinones were isolated from the methanolic extract of the brown alga, Sargassum micracanthum. Their structures were elucidated based on spectroscopic analysis and chemical conversions from 2-geranylgeranyl-6-methyl-1,4-benzohydroquinone. These plastoquinones exhibited significant antioxidant activities such as an inhibitory effect on lipid peroxidation and a radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH). Some of the new plastoquiones showed cytotoxic activity against cancer cell line.
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