期刊
FRONTIERS IN BIOSCIENCE-LANDMARK
卷 10, 期 -, 页码 2750-2757出版社
IMR PRESS
DOI: 10.2741/1732
关键词
inflammation; thrombosis; vascular disease; inflammatory mediators; thrombogenesis; tissue factor; adhesion molecules; microparticles; review
Vessel wall endothelial damage initiates a local inflammatory response, which promotes a prothrombotic state driven by tissue factor, adhesion molecules, and proinflammatory cytokines. Understanding how natural inflammatory mechanisms promote a procoagulant state, may lead to the development of new pharmacological interventions targeted at thrombosis.
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