期刊
MOVEMENT DISORDERS
卷 20, 期 9, 页码 1220-1223出版社
WILEY
DOI: 10.1002/mds.20502
关键词
chorea; Creutzfeldt-Jakob disease; epilepsia partialis continua
Movement disorders and epilepsy rarely occur in the early stage of Creutzfeldt-Jakob disease (CJD) but have not been reported concurrently. We report on a 47-year-old patient with probable CJD who presented with generalized chorea and focal dystonia with myoclonic jerks on the right hand. Myoclonic jerks progressed to epilepsia partialis continua within 5 days of admission to the hospital. The diagnosis of our patient was compatible with probable CJD on the basis of clinical course, electroencephalogram, and diffusion-weighted magnetic resonance imaging findings, and presence of 14-3-3 protein in cerebrospinal fluid. To our knowledge, this is the first report of a case developing both movement disorders and epilepsia partialis continua in the early stage of the disease. (C) 2005 Movement Disorder Society.
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