4.8 Article

De novo asymmetric synthesis of daumone via a palladium-catalyzed glycosylation

期刊

ORGANIC LETTERS
卷 7, 期 18, 页码 3921-3924

出版社

AMER CHEMICAL SOC
DOI: 10.1021/ol051383e

关键词

-

向作者/读者索取更多资源

The enantioselective syntheses of daumone and two analogues have been achieved in seven to eight steps. This route relies upon a diasteroselective palladium-catalyzed glycosylation reaction for the formation of the anomeric bond. The asymmetry of the sugar and aglycone portion of daumone were introduced by Noyori reduction of an acylfuran and a propargyl ketone. A highly diastereoselective epoxidation and reductive ring opening established the desired C-2 and C-4 stereochemistry of daumone.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据