Optic nerve sheath diameter does not change with patient position

Objectives: Optic nerve sheath diameter (ONSD) has been proposed as a marker for increased intracranial pressure. Trendelenburg's position is often used in hypotensive patients and reverse Trendelenburg's position (30 degrees head up) is often used in head injury patients. We asked if there would be any change in OSND in healthy human adults between the supine, Trendelenburg's, and reverse Trendelenburg's positions. Methods: Prospective case-control blinded study using consenting healthy adults. Three separate investigators measured the ONSD in each eye of 10 separate volunteers in the supine, Trendelenburg's, and reverse Trendelenburg's positions with 30 degrees angulation from the horizontal. Data were analyzed using the paired t test. Results: In the supine position, the mean ONSD was 4.6 +/- 0.71 (SD) mm in the right eye and 4.5 +/- 0.56 (SD) min in the left eye. In Trendelenburg's position, the mean ONSD was 4.4 +/- 0.72 (SD) min in the right eye and 4.7 +/- 0.53 (SD) turn in the left eye. In reverse Trendelenburg's position, the mean ONSD was 4.4 +/- 0.49 (SD) min in the right eye and 4.8 +/- 0.76 (SD) mm in the left eye. There was no significant difference in OSND between positions for either eye by analysis of variance. Interobserver agreement was +/-1 min in at least 90% of the subjects regardless of position. Conclusion: Optic nerve sheath diameter measurement by ultrasound does not significantly change with Trendelenburg's or reverse Trendelenburg's position in comparison with the supine position in healthy individuals. (C) 2005 Elsevier Inc. All rights reserved.