期刊
BIOMETALS
卷 18, 期 5, 页码 475-481出版社
SPRINGER
DOI: 10.1007/s10534-005-1245-0
关键词
cadmium; plants; cell proliferation; cell cycle; apoptosis
Cadmium is a heavy metal, which is classified as a human carcinogen and is known to be toxic to plants. However, plants do not respond to this metal by massive cell proliferation. In this review the various aspects of cadmium toxicity in plants are compared to related processes in mammalian cells. The following issues are discussed: cellular uptake of Cd ions, their intracellular transport, the effects on cellular signaling, nucleic acids and proteins, modi. cation of gene expression, cell cycle control and apoptosis. Reviewed data suggest that such features as: ability to remove the oxidized proteins, slightly different regulation of cell cycle genes, specific pattern of apoptosis, makes plants resistant to Cd2+-induced uncontrolled cell proliferation.
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