期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 49, 期 10, 页码 4354-4357出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.49.10.4354-4357.2005
关键词
-
资金
- NIAID NIH HHS [AI053195, R15 AI053195, R01 AI051486, AI1051486] Funding Source: Medline
We have isolated in vitro fluoroquinolone-resistant mutants of the Lyme disease agent, Borrelia burgdorferi. Mutations in parC, which encodes a subunit of topoisomerase IV, were associated with loss of susceptibility to sparfloxacin, moxifloxacin, and Bay-Y3118, but not ciprofloxacin. This is the first description of fluoroquinolone resistance in the spirochete phylum.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据