期刊
DEVELOPMENTAL BIOLOGY
卷 286, 期 1, 页码 57-77出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ydbio.2005.07.006
关键词
insect appendages; appendage primordia; limb axis specification; Distal-less; appendage patterning; appendage allometry; comparative developmental genetics
It is arguable that the evolutionary and ecological success of insects is due in large part to the versatility of their articulated appendages. Recent advances in our understanding of appendage development in Drosophila melanogaster, as well as functional and expression studies in other insect species have begun to frame the general themes of appendage development in the insects. Here, we review current studies that provide for a comparison of limb developmental mechanisms acting at five levels: (1) the specification of ventral appendage primordia; (2) specification of the limb axes; (3) regulation and interactions of genes expressed in specific domains of the proximal-distal axis, such as Distal-less; (4) the specification of appendage identity; and (5) genetic regulation of appendage allometry. (c) 2005 Elsevier Inc. All rights reserved.
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