期刊
ANTIVIRAL RESEARCH
卷 94, 期 3, 页码 242-257出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.antiviral.2012.04.002
关键词
Alphavirus; Arbovirus; Genetics; Ecology; Epidemiology; Biodefense
资金
- Department of Homeland Security [HSHQDC-09-C-00120]
- NIH [R01-AI071192, R01-AI069145, R01AI093491, U54-AI057156]
Alphaviruses are responsible for several medically important emerging diseases and are also significant veterinary pathogens. Due to the aerosol infectivity of some alphaviruses and their ability to cause severe, sometimes fatal neurologic diseases, they are also of biodefense importance. This review discusses the ecology, epidemiology and molecular virology of the alphaviruses, then focuses on three of the most important members of the genus: Venezuelan and eastern equine encephalitis and chikungunya viruses, with emphasis on their genetics and emergence mechanisms, and how current knowledge as well as gaps influence our ability to detect and determine the source of both natural outbreaks and potential use for bioterrorism. This article is one of a series in Antiviral Research on the genetic diversity of emerging viruses. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据