期刊
PHYSIOLOGY
卷 20, 期 -, 页码 349-356出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00025.2005
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The bone marrow vasuclar niche consists of a network of thin-walled and fenestrated sinusoidal vessels whose integrity is maintained and supported by surrounding hematopoietic cells. However, this dependence is highly reciprocal in that the bone marrow vasculature provides not only a conduit for mature hematopoietic cells to the peripheral circulation but also a site where hematopoietic progenitors, especially megakaryocytes, differentiate and set the stage for full reconstitution of hematopoiesis.
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