期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 16, 期 5, 页码 577-583出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2005.08.009
关键词
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Biologically mediated processes seem promising for energy conversion, in particular for the conversion of lignocellulosic biomass into fuels. Although processes featuring a step dedicated to the production of cellulase enzymes have been the focus of most research efforts to date, consolidated bioprocessing (CBP) - featuring cellulase production, cellulose hydrolysis and fermentation in one step - is an alternative approach with outstanding potential. Progress in developing CBP-enabling microorganisms is being made through two strategies: engineering naturally occurring cellulolytic microorganisms to improve product-related properties, such as yield and titer, and engineering non-cellulolytic organisms that exhibit high product yields and titers to express a heterologous cellulase system enabling cellulose utilization. Recent studies of the fundamental principles of microbial cellulose utilization support the feasibility of CBP.
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