期刊
ACTA PAEDIATRICA
卷 94, 期 10, 页码 1507-1509出版社
WILEY
DOI: 10.1080/08035250510039838
关键词
systemic lupus erythematosus; child; membranous glomerulonephritis; intravenous cyclophosphamide; prednisolone
类别
The authors report the case of a 10-y-old girl with clinical diagnosis of systemic lupus erythematosus (SLE), made at the age of 6 y, based upon arthritis, serositis, haematological disorder and positive antinuclear antibody. The first manifestation of disease-Raynaud's phenomenon-appeared at the age of 4 y. Seven months after the diagnosis, she developed nephrotic proteinuria with haematuria. Percutaneous renal biopsy showed membranous glomerulonephritis, the least common form of lupus nephritis. Conclusion: Intravenous cyclophosphamide therapy associated with oral prednisolone proved effective in inducing complete remission of nephrotic syndrome.
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