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David M. Harris et al.
CLINICAL SCIENCE (2008)
Mechanisms underlying developmental programming of elevated blood pressure and vascular dysfunction: evidence from human studies and experimental animal models
Anne Monique Nuyt
CLINICAL SCIENCE (2008)
Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase
Tomoko Nishino et al.
FEBS JOURNAL (2008)
Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells
Desmond B. Jay et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Novel redox-dependent regulation of NOX5 by the tyrosine kinase c-Abl
Amina El Jamali et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Hypoxia activates NADPH oxidase to increase [ROS]i and [Ca2+]i through the mitochondrial ROS-PKCε signaling axis in pulmonary artery smooth muscle cells
Rakesh Rathore et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
The interaction between coronary endothelial dysfunction, local oxidative stress, and endogenous nitric oxide in humans
Shahar Lavi et al.
HYPERTENSION (2008)
Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension
Alvaro Yogi et al.
HYPERTENSION (2008)
Vitamins E and C in the Prevention of Cardiovascular Disease in Men The Physicians' Health Study II Randomized Controlled Trial
Howard D. Sesso et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)
Regulation of ROS signal transduction by NADPH oxidase 4 localization
Kai Chen et al.
JOURNAL OF CELL BIOLOGY (2008)
NOX5, a New Radical Player in Human Atherosclerosis?
Eberhard Schulz et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Calcium-Dependent NOX5 Nicotinamide Adenine Dinucleotide Phosphate Oxidase Contributes to Vascular Oxidative Stress in Human Coronary Artery Disease
Tomasz J. Guzik et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Peroxynitrite is involved in the dysfunction of vasorelaxation in SHR/NDmcr-cp rats, spontaneously hypertensive obese rats
Satomi Kagota et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2007)
NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation
Lena Serrander et al.
BIOCHIMIE (2007)
NOX5 variants are functionally active in endothelial cells
Rachida S. BelAiba et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice
D. Adlam et al.
EXPERIMENTAL PHYSIOLOGY (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
PHYSIOLOGICAL REVIEWS (2007)
Oxidative stress in human in sustained and white coat hypertension
M. Caner et al.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2006)
Mechanisms of disease:: oxidative stress and inflammation in the pathogenesis of hypertension
Nosratola D. Vaziri et al.
NATURE CLINICAL PRACTICE NEPHROLOGY (2006)
NADPH oxidases: New kids on the block
Miklos Geiszt
CARDIOVASCULAR RESEARCH (2006)
The C242T CYBA polymorphism of NADPH oxidase is associated with essential hypertension
Maria U. Moreno et al.
JOURNAL OF HYPERTENSION (2006)
Byproducts of oxidative protein damage and antioxidant enzyme activities in plasma of patients with different degrees of essential hypertension
DV Simic et al.
JOURNAL OF HUMAN HYPERTENSION (2006)
RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response
P Modlinger et al.
HYPERTENSION (2006)
Coronary artery superoxide production and nox isoform expression in human coronary artery disease
TJ Guzik et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Decreased blood pressure in NOX1-deficient mice
G Gavazzi et al.
FEBS LETTERS (2006)
Role of extracellular superoxide dismutase in hypertension
Maria Carolina Gongora et al.
HYPERTENSION (2006)
Nox1 is involved in angiotensin II-mediated hypertension - A study in Nox1-deficient mice
K Matsuno et al.
CIRCULATION (2005)
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice
A Dikalova et al.
CIRCULATION (2005)
Calcium channel blockades exhibit anti-inflammatory and antioxidative effects by augmentation of endothelial nitric oxide synthase and the inhibition of angiotensin converting enzyme in the NG-nitro-L-arginine methyl ester-induced hypertensive rat aorta:: Vasoprotective effects beyond the blood pressure-lowering effects of amlodipine and manidipine
H Toba et al.
HYPERTENSION RESEARCH (2005)
Ascorbic acid selectively improves large elastic artery compliance in postmenopausal women
KL Moreau et al.
HYPERTENSION (2005)
Superoxide mediates angiotensin II-induced influx of extracellular calcium in neural cells
MC Zimmerman et al.
HYPERTENSION (2005)
Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase
RM Touyz et al.
HYPERTENSION (2005)
p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells - Role in NAD(P)H oxidase regulation by angiotensin II
RM Touyz et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Impact of regular physical activity on the NAD(P)H oxidase and angiotensin receptor system in patients with coronary artery disease
V Adams et al.
CIRCULATION (2005)
Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humans
JD Morrow
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
The HOPE (Heart Outcomes Prevention Evaluation) study and its consequences
MJ McQueen et al.
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION (2005)
NADPH oxidase-mediated oxidative stress: Genetic studies of the p22(phox) gene in hypertension
G Zalba et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22(phox) in mice
K Laude et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5)
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension
O Jung et al.
CIRCULATION (2004)
Effects of vitamin E on cardiovascular outcomes in people with mild-to-moderate renal insufficiency: Results of the HOPE study
JFE Mann et al.
KIDNEY INTERNATIONAL (2004)
Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells
LL Hilenski et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Recent trials of antioxidant therapy: What should we be tellmg our patients?
BI Hasnain et al.
CLEVELAND CLINIC JOURNAL OF MEDICINE (2004)
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice
A Virdis et al.
JOURNAL OF HYPERTENSION (2004)
Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins
TJ Guzik et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Effects of long-term daily low-dose supplementation with antioxidant vitamins and minerals on structure and function of large arteries
M Zureik et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats
F Tabet et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2004)
Reactive oxygen species in vascular biology: implications in hypertension
RM Touyz et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2004)
Vascular NAD(P)H oxidases:: specific features, expression, and regulation
B Lassègue et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2003)
DASH diet lowers blood pressure and lipid-induced oxidative stress in obesity
HF Lopes et al.
HYPERTENSION (2003)
Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension
RM Touyz et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2003)
Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes
BA Mullan et al.
HYPERTENSION (2002)
Role of p47phox in vascular oxidative stress and hypertension caused by angiotensin II
U Landmesser et al.
HYPERTENSION (2002)
Angiotensin II stimulation of NAD(P)H oxidase activity - Upstream mediators
PN Seshiah et al.
CIRCULATION RESEARCH (2002)
Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries - Regulation by angiotensin II
RM Touyz et al.
CIRCULATION RESEARCH (2002)
Mechanisms of increased vascular superoxide production in human diabetes mellitus Role of NAD(P)H oxidase and endothelial nitric oxide synthase
TJ Guzik et al.
CIRCULATION (2002)
Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR
X Chen et al.
HYPERTENSION (2001)
Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O2- and systolic blood pressure in mice
FE Rey et al.
CIRCULATION RESEARCH (2001)
Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways
RM Touyz et al.
JOURNAL OF HYPERTENSION (2001)
Plasma hydrogen peroxide production in human essential hypertension -: Role of heredity, gender, and ethnicity
F Lacy et al.
HYPERTENSION (2000)
Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
KK Griendling et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
Identification of Renox, an NAD(P)H oxidase in kidney
M Geiszt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats
G Zalba et al.
HYPERTENSION (2000)