期刊
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
卷 53, 期 2, 页码 93-99出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2005.05.015
关键词
Escherichia coli; bacteremia; pyelonephritis; virulence factors; phylogenetic groups; compromise status
To assess the role of phylogenetic background and putative virulence factors (VFs) in Escherichia coli causing urinary bacteremia, 50 strains isolated from this condition were compared with 50 strains isolated from pyelonephritis and 50 from other sources of bacteremia. papA and papGII were significantly more prevalent in urinary bacteremia and pyelonephritis (78%, 66% and 70%, 58%) than in other-source bacteremia (48% and 24%), whereas sfa/focDE and cnfl were more prevalent in urinary-source bacteremia (56% and 44%) than in pyelonephritis and other-source bacteremia (28%, 42% and 20%, 28%). Group 132 was the most frequent in all conditions (63% of isolates) and exhibited the greatest concentration of VFs. Urinary tract bacteremia, pyelonephritis, and other-source bacteremia isolates presented similar virulence scores (7.8, 7.0, and 6.6); however, there were striking differences among the phylogenetic groups (8.7 in group B2 versus 3.4 in group A; P <.001). Group A and B I strains almost exclusively infected compromised hosts. (c) 2005 Elsevier Inc. All rights reserved.
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