4.7 Article

The Gasotransmitter Hydrogen Sulfide Induces Nrf2-Target Genes by Inactivating the Keap1 Ubiquitin Ligase Substrate Adaptor Through Formation of a Disulfide Bond Between Cys-226 and Cys-613

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

High Turnover Rates for Hydrogen Sulfide Allow for Rapid Regulation of Its Tissue Concentrations

Victor Vitvitsky et al.

ANTIOXIDANTS & REDOX SIGNALING (2012)

Review Biochemistry & Molecular Biology

Hydrogen Sulfide Is a Signaling Molecule and a Cytoprotectant

Hideo Kimura et al.

ANTIOXIDANTS & REDOX SIGNALING (2012)

Article Cell Biology

Somatic mutations of the KEAP1 gene in common solid cancers

Nam Jin Yoo et al.

HISTOPATHOLOGY (2012)

Article Biochemistry & Molecular Biology

Nrf2-dependent Induction of Proteasome and Pa28αβ Regulator Are Required for Adaptation to Oxidative Stress

Andrew M. Pickering et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

Comprehensive genomic characterization of squamous cell lung cancers

Peter S. Hammerman et al.

NATURE (2012)

Article Biochemistry & Molecular Biology

Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

Brian N. Chorley et al.

NUCLEIC ACIDS RESEARCH (2012)

Review Oncology

NRF2 and cancer: the good, the bad and the importance of context

Michael B. Sporn et al.

NATURE REVIEWS CANCER (2012)

Review Pharmacology & Pharmacy

Hydrogen Sulfide and Cell Signaling

Ling Li et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 51, 2011 (2011)

Article Biochemistry & Molecular Biology

The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues

Omer Kabil et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Article Biochemistry & Molecular Biology

Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice

Weihong Han et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Review Biochemistry & Molecular Biology

Basic Principles and Emerging Concepts in the Redox Control of Transcription Factors

Regina Brigelius-Flohe et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Article Biochemistry & Molecular Biology

The reaction of H2S with oxidized thiols: Generation of persulfides and implications to H2S biology

Nestor E. Francoleon et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)

Article Biochemistry & Molecular Biology

Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide

Yoshinori Mikami et al.

BIOCHEMICAL JOURNAL (2011)

Article Cell Biology

Mitochondrial Complex III ROS Regulate Adipocyte Differentiation

Kathryn V. Tormos et al.

CELL METABOLISM (2011)

Article Biochemistry & Molecular Biology

Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism

Emilia Kansanen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

Navasona Krishnan et al.

SCIENCE SIGNALING (2011)

Review Biochemistry & Molecular Biology

Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches

Candice E. Paulsen et al.

ACS CHEMICAL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Cancer Chemoprevention Mechanisms Mediated Through the Keap1-Nrf2 Pathway

John D. Hayes et al.

ANTIOXIDANTS & REDOX SIGNALING (2010)

Review Biochemistry & Molecular Biology

Regulation of the Nrf2-Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

Nicole F. Villeneuve et al.

ANTIOXIDANTS & REDOX SIGNALING (2010)

Article Biochemistry & Molecular Biology

Reexamination of the electrophile response element sequences and context reveals a lack of consensus in gene function

Hongqiao Zhang et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2010)

Article Biochemistry & Molecular Biology

Activation of NRF2 by Nitrosative Agents and H2O2 Involves KEAP1 Disulfide Formation

Simon Fourquet et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

The Critical Role of Nitric Oxide Signaling, via Protein S-Guanylation and Nitrated Cyclic GMP, in the Antioxidant Adaptive Response

Shigemoto Fujii et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Hydrogen sulfide as a gasotransmitter

Moataz M. Gadalla et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Review Biochemistry & Molecular Biology

Dietary isoflavones and vascular protection: Activation of cellular antioxidant defenses by SERMs or hormesis?

Richard C. M. Siow et al.

MOLECULAR ASPECTS OF MEDICINE (2010)

Article Multidisciplinary Sciences

Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

Michael McMahon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains

Toshihiko Ogura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

Norihiro Shibuya et al.

ANTIOXIDANTS & REDOX SIGNALING (2009)

Article Biochemistry & Molecular Biology

H2S Protects Against Methionine-Induced Oxidative Stress in Brain Endothelial Cells

Neetu Tyagi et al.

ANTIOXIDANTS & REDOX SIGNALING (2009)

Article Cardiac & Cardiovascular Systems

Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

John W. Calvert et al.

CIRCULATION RESEARCH (2009)

Article Biochemistry & Molecular Biology

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

Makoto Kobayashi et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

H2S Signals Through Protein S-Sulfhydration

Asif K. Mustafa et al.

SCIENCE SIGNALING (2009)

Review Biochemistry & Molecular Biology

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

John D. Hayes et al.

TRENDS IN BIOCHEMICAL SCIENCES (2009)

Article Biochemistry & Molecular Biology

Keap1 modification and nuclear accumulation in response to S-nitrosocysteine

Barbara J. Buckley et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Article Biochemistry & Molecular Biology

Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid

Freddie R. Salsbury et al.

PROTEIN SCIENCE (2008)

Article Biochemical Research Methods

Sites of alkylation of human Keap1 by natural Chemoprevention agents

Yan Luo et al.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2007)

Article Biochemistry & Molecular Biology

Biochemistry of oxidative stress

B. Halliwell

BIOCHEMICAL SOCIETY TRANSACTIONS (2007)

Article Biochemistry & Molecular Biology

Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin

Shunsuke Tanigawa et al.

FREE RADICAL BIOLOGY AND MEDICINE (2007)

Article Biochemistry & Molecular Biology

The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin

Goedele Roos et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Hydrogen sulfide protects HT22 neuronal cells from oxidative stress

Yuka Kimura et al.

ANTIOXIDANTS & REDOX SIGNALING (2006)

Article Pharmacology & Pharmacy

Molecular mechanisms of hydrogen sulfide toxicity

Don H. Truong et al.

DRUG METABOLISM REVIEWS (2006)

Article Biochemistry & Molecular Biology

ets-1 is transcriptionally up-regulated by H2O2 via an antioxidant response element

LA Wilson et al.

FASEB JOURNAL (2005)

Article Biochemistry & Molecular Biology

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation

F Hong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Modifying specific cysteines of the electrophile-sensing human Keap1 disrupt binding to the protein is insufficient to Nrf2 domain Neh2

AL Eggler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B

TC Meng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2

A Kobayashi et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Production of the neuromodulator H2S by cystathionine β-synthase via the condensation of cysteine and homocysteine

XL Chen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

DD Zhang et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Physiology

Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia

V Vitvitsky et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2004)

Article Multidisciplinary Sciences

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

AT Dinkova-Kostova et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)