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Bo Zhang et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Involvement of Thio-, Peroxi-, and Glutaredoxins in Cellular Redox-Dependent Processes
E. V. Kalinina et al.
BIOCHEMISTRY-MOSCOW (2008)
Evaluation of oxidative stress in colorectal cancer patients
Dong Chang et al.
BIOMEDICAL AND ENVIRONMENTAL SCIENCES (2008)
Collagen density promotes mammary tumor initiation and progression
Paolo P. Provenzano et al.
BMC MEDICINE (2008)
Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2
B. H. Y. Yeung et al.
BRITISH JOURNAL OF CANCER (2008)
Cancer cell killing via ROS To increase or decrease, that is the question
Jie Wang et al.
CANCER BIOLOGY & THERAPY (2008)
Tumor cell metabolism: Cancer's Achilles' heel
Guido Kroemer et al.
CANCER CELL (2008)
Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy
Masuko Ushio-Fukai et al.
CANCER LETTERS (2008)
Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice
Antje Banning et al.
CANCER RESEARCH (2008)
Tumor escape mechanism governed by myeloid-derived suppressor cells
Srinivas Nagaraj et al.
CANCER RESEARCH (2008)
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy
Anju Singh et al.
CANCER RESEARCH (2008)
The role of hypoxia-inducible factors in tumorigenesis
E. B. Rankin et al.
CELL DEATH AND DIFFERENTIATION (2008)
Mitochondrial complex III regulates hypoxic activation of HIF
T. Klimova et al.
CELL DEATH AND DIFFERENTIATION (2008)
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
Ralph J. DeBerardinis et al.
CELL METABOLISM (2008)
The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages
Paola Allavena et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2008)
Increased oxidative stress created by adenoviral MnSOD or CuZnSOD plus BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) inhibits breast cancer cell growth
Christine J. Weydert et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation
J. A. Coulter et al.
GENE THERAPY (2008)
Oxidative stress-inducible lentiviral vectors for gene therapy
H. Hurttila et al.
GENE THERAPY (2008)
Oxidative stress caused by blocking of mitochondrial Complex IH+ pumping as a link in aging/disease vicious cycle
Andrea Dlaskova et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
The redox state of the lung cancer microenvironment depends on the levels of thioredoxin expressed by tumor cells and affects tumor progression and response to prooxidants
Jenny Ceccarelli et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
R Regulation of tumor angiogenesis and metastasis by FGF and PDGF signaling pathways
Yihai Cao et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2008)
Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?
Brian D. Lawenda et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
William G. Kaelin et al.
MOLECULAR CELL (2008)
Pyruvate kinase M2 is a phosphotyrosine-binding protein
Heather R. Christofk et al.
NATURE (2008)
Silencing of peroxiredoxin 3 and peroxiredoxin 5 reveals the role of mitochondrial peroxiredoxins in the protection of human neuroblastoma SH-SY5Y cells toward MPP+
Stephanie De Simoni et al.
NEUROSCIENCE LETTERS (2008)
Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling
N. M. Reddy et al.
ONCOGENE (2008)
Hypoxia and aggressive tumor phenotype: Implications for therapy and prognosis
Peter Vaupel
ONCOLOGIST (2008)
Dual roles of Nrf2 in cancer
Alexandria Lau et al.
PHARMACOLOGICAL RESEARCH (2008)
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
Kaori Ishikawa et al.
SCIENCE (2008)
Macrophage polarization in tumour progression
Antonio Sica et al.
SEMINARS IN CANCER BIOLOGY (2008)
PPAR gamma and Proline Oxidase in Cancer
James M. Phang et al.
PPAR RESEARCH (2008)
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Mark W. Dewhirst et al.
NATURE REVIEWS CANCER (2008)
The cystine/cysteine cycle:: a redox cycle regulating susceptibility versus resistance to cell death
A. Banjac et al.
ONCOGENE (2008)
HYPOXIA AND METABOLISM SERIES - TIMELINE The impact of O2 availability on human cancer
Jessica A. Bertout et al.
NATURE REVIEWS CANCER (2008)
The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
William G. Kaelin
NATURE REVIEWS CANCER (2008)
Nipple aspirate fluids from women with breast cancer contain increased levels of group IIa secretory phospholipase A2
Ferdinando Mannello et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
Hypoxia, HIF1 and glucose metabolism in the solid tumour
Nicholas C. Denko
NATURE REVIEWS CANCER (2008)
Hypoxia, DNA repair and genetic instability
Robert G. Bristow et al.
NATURE REVIEWS CANCER (2008)
Modulation of reactive oxygen species in pancreatic cancer
Melissa L. T. Teoh et al.
CLINICAL CANCER RESEARCH (2007)
Targeting NOX, INOS and COX-2 in inflammatory cells: Chemoprevention using food phytochemicals
Akira Murakami et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens
Aya Naiki-Ito et al.
CANCER RESEARCH (2007)
Heme oxygenase-1 in tumors: Is it a false friend?
Alicja Jozkowicz et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Chronic inflammation and oxidative stress in human carcinogenesis
Alessandro Federico et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Thioredoxin, produced by stromal cells retrieved from the lymph node microenvironment, rescues chronic lymphocytic leukemia cells from apoptosis in vitro
Eva Backman et al.
HAEMATOLOGICA (2007)
Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication
Min-Hyuk Yoo et al.
PLOS ONE (2007)
Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma
Ake Oldberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Are peroxiredoxins tumor suppressors?
Carola Anke Neumann et al.
CURRENT OPINION IN PHARMACOLOGY (2007)
Urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG) and genetic polymorphisms in breast cancer patients
Hsien-Wen Kuo et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2007)
From selenium to selenoproteins: Synthesis, identity, and their role in human health
Laura Vanda Papp et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter
Hua-Jung Li et al.
CANCER RESEARCH (2007)
Hypoxia-inducible factors, stem cells, and cancer
Brian Keith et al.
CELL (2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
Mitochondrial nitric oxide in the signaling of cell integrated responses
Maria Cecilia Carreras et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production
Juan M. Funes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hypoxia signalling controls metabolic demand
M. Christiane Brahimi-Horn et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity
Wei-Qun Ding et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Integrin-mediated cell adhesion and spreading engage different sources of reactive oxygen species
Maria Letizia Taddei et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Relationship between DNA damage and total antioxidant capacity in patients with glioblastoma multiforme
S. Tuzgen et al.
CLINICAL ONCOLOGY (2007)
Excessive superoxide anion generation plays a key role in carcinogenesis
Miguel Lopez-Lazaro
INTERNATIONAL JOURNAL OF CANCER (2007)
Effects of MnSOD-plasmid liposome gene therapy on antioxidant levels in irradiated murine oral cavity orthotopic tumors
Michael W. Epperly et al.
RADIATION RESEARCH (2007)
Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage
Hiroko P. Indo et al.
MITOCHONDRION (2007)
Reactive oxygen species: A breath of life or death?
John P. Fruehauf et al.
CLINICAL CANCER RESEARCH (2007)
被撤回的出版物: Biomarkers for oxidative stress status of DNA, lipids, and proteins in vitro and in vivo cancer research (Retracted article. See vol 241, pg 98, 2007)
Eun-Sun Hwang et al.
TOXICOLOGY (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
PHYSIOLOGICAL REVIEWS (2007)
Salivary analysis in oral cancer patients - DNA and protein oxidation, reactive nitrogen species, and antioxidant profile
Gideon Bahar et al.
CANCER (2007)
Oxidative stress and apoptosis: impact on cancer therapy
Tomris Ozben
JOURNAL OF PHARMACEUTICAL SCIENCES (2007)
Alternative vascularization mechanisms in cancer - Pathology and therapeutic implications
Balazs Dome et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Free radicals and antioxidants in normal physiological functions and human disease
Marian Valko et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
The thioredoxin system in cancer
Elias S. J. Arner et al.
SEMINARS IN CANCER BIOLOGY (2006)
Collagen-based co-culture for invasive study on cancer cells-fibroblasts interaction
Zhong Min Che et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Redox signaling in angiogenesis: Role of NADPH oxidase
Masuko Ushio-Fukai
CARDIOVASCULAR RESEARCH (2006)
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells
T. Mochizuki et al.
ONCOGENE (2006)
Acid-mediated tumor invasion: a multidisciplinary study
RA Gatenby et al.
CANCER RESEARCH (2006)
Complete elimination of colorectal tumor xenograft by combined manganese superoxide dismutase with tumor necrosis factor-related apoptosis-inducing ligand gene virotherapy
YH Zhang et al.
CANCER RESEARCH (2006)
Hydrogen peroxide: A signaling messenger
James R. Stone et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Bone-marrow haematopoietic-stem-cell niches
A Wilson et al.
NATURE REVIEWS IMMUNOLOGY (2006)
Inhibition of lung tumor growth and augmentation of radiosensitivity by decreasing peroxiredoxin I expression
MF Chen et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
Mechanistic studies of the Nrf2-Keap1 signaling pathway
Donna D. Zhang
DRUG METABOLISM REVIEWS (2006)
Suppression of the malignant phenotype in pancreatic cancer by overexpression of phospholipid hydroperoxide glutathione peroxidase
JR Liu et al.
HUMAN GENE THERAPY (2006)
Paradoxical roles of the immune system during cancer development
KE de Visser et al.
NATURE REVIEWS CANCER (2006)
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
RN Kaplan et al.
NATURE (2005)
Endogenous thioredoxin is required for redox cycling of anthracyclines and p53-dependent apoptosis in cancer cells
D Ravi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The pH dependence of NADPH oxidase in human eosinophils
D Morgan et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
High thioredoxin expression is associated with resistance to docetaxel in primary breast cancer
SJ Kim et al.
CLINICAL CANCER RESEARCH (2005)
Mitochondrial manganese-superoxide dismutase expression in ovarian cancer
YM Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The role of peroxiredoxin II in radation-resistant MCF-7 breast cancer cells
TL Wang et al.
CANCER RESEARCH (2005)
Superoxide anion radical, lipid peroxides and antioxidant status in the blood of patients with breast cancer
CC Yeh et al.
CLINICA CHIMICA ACTA (2005)
Pyruvate kinase type M2 and its role in tumor growth and spreading
S Mazurek et al.
SEMINARS IN CANCER BIOLOGY (2005)
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
DC Radisky et al.
NATURE (2005)
Secreted protein acidic and rich in cysteine produced by human melanoma cells modulates polymorphonuclear leukocyte recruitment and antitumor cytotoxic capacity
MJ Alvarez et al.
CANCER RESEARCH (2005)
Extracellular matrix (ECM) microstructural composition regulates local cell-ECM biomechanics and fundamental fibroblast behavior: a multidimensional perspective
AM Pizzo et al.
JOURNAL OF APPLIED PHYSIOLOGY (2005)
Combined efficacy of tamoxifen and coenzyme Q10 on the status of lipid peroxidation and antioxidants in DMBA induced breast cancer
SS Perumal et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2005)
Mechanism of the tumor suppressive effect of MnSOD overexpression
LW Oberley
BIOMEDICINE & PHARMACOTHERAPY (2005)
Mitochondrial O2-• and H2O2 mediate glucose deprivation-induced cytotoxicity and oxidative stress in human cancer cells
IM Ahmad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
JS Ungerstedt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
NADPH oxidase and endothelial cell function
R Ray et al.
CLINICAL SCIENCE (2005)
Physiological roles of xanthine oxidoreductase
R Harrison
DRUG METABOLISM REVIEWS (2004)
Superoxide dismutases in malignant cells and human tumors
VL Kinnula et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Redox regulation of pancreatic cancer cell growth: Role of glutathione peroxidase in the suppression of the malignant phenotype
JR Liu et al.
HUMAN GENE THERAPY (2004)
Nox enzymes and the biology of reactive oxygen
JD Lambeth
NATURE REVIEWS IMMUNOLOGY (2004)
Oxidative protein folding in eukaryotes: mechanisms and consequences
BP Tu et al.
JOURNAL OF CELL BIOLOGY (2004)
Imbalance of antioxidant enzymes in tumor cells and inhibition of proliferation and malignant features by scavenging hydrogen peroxide
L Policastro et al.
MOLECULAR CARCINOGENESIS (2004)
Mechanisms that regulate production of reactive oxygen species by cytochrome P450
RC Zangar et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
Oxidative DNA damage and disease: induction, repair and significance
MD Evans et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2004)
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2
A Kobayashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Mutant K-rasV12 increases COX-2, peroxides and DNA damage in lung cells
A Maciag et al.
CARCINOGENESIS (2004)
Exploiting tumour hypoxia in cancer treatment
JM Brown et al.
NATURE REVIEWS CANCER (2004)
Lipid peroxidation and protein oxidation in patients affected by Hodgkin's lymphoma
F Morabito et al.
MEDIATORS OF INFLAMMATION (2004)
NK cells and the tumour microenvironment: implications for NK-cell function and anti-tumour activity
PA Albertsson et al.
TRENDS IN IMMUNOLOGY (2003)
Chromosome aberrations in solid tumors
DG Albertson et al.
NATURE GENETICS (2003)
Tumorigenesis and the angiogenic switch
G Bergers et al.
NATURE REVIEWS CANCER (2003)
Structure, mechanism and regulation of peroxiredoxins
ZA Wood et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
Probing the structural and molecular diversity of tumor vasculature
R Pasqualini et al.
TRENDS IN MOLECULAR MEDICINE (2002)
Topology of superoxide production from different sites in the mitochondrial electron transport chain
J St-Pierre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2002)
Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases
E Werner et al.
JOURNAL OF CELL BIOLOGY (2002)
Efficient mobilization and recruitment of marrow-derrived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors
S Rafii et al.
GENE THERAPY (2002)
Reactive oxygen generated by Nox1 triggers the angiogenic switch
JL Arbiser et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
S Morikawa et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Mn-SOD antisense upregulates in vivo apoptosis of squamous cell carcinoma cells by anticancer drugs and γ-rays regulating expression of the Bcl-2 family proteins, COX-2 and p21
E Ueta et al.
INTERNATIONAL JOURNAL OF CANCER (2001)
Inflammation and cancer: back to Virchow?
F Balkwill et al.
LANCET (2001)
Angiogenesis in cancer and other diseases
P Carmeliet et al.
NATURE (2000)
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia -: A mechanism of O2 sensing
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A threshold concept for cancer therapy
Q Kong et al.
MEDICAL HYPOTHESES (2000)
Openings between defective endothelial cells explain tumor vessel leakiness
H Hashizume et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Vasculogenic mimicry and tumor angiogenesis
R Folberg et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
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