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Oxidative stress and pathogenesis of inflammatory bowel disease: An epiphenomenon or the cause?
Ali Rezaie et al.
DIGESTIVE DISEASES AND SCIENCES (2007)
Prohibitin protects against oxidative stress in intestinal epithelial cells
Arianne L. Theiss et al.
FASEB JOURNAL (2007)
4-Hydroxy-2-alkenals in polyunsaturated fatty acids-fortified infant formulas and other commercial food products
J. Surh et al.
FOOD ADDITIVES AND CONTAMINANTS (2007)
Immune dysfunction in inflammatory bowel disease
Manuela G. Neuman
TRANSLATIONAL RESEARCH (2007)
Dietary advanced lipid oxidation endproducts are risk factors to human health
Joseph Kanner
MOLECULAR NUTRITION & FOOD RESEARCH (2007)
Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis
Tin Oo Khor et al.
CANCER RESEARCH (2006)
Proteasome-mediated degradation of IκBα and processing of p105 in Crohn disease and ulcerative colitis
Alexander Visekruna et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease
Christoph Moehle et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Curcumin maintenance therapy for ulcerative colitis: Randomized, multicenter, double-blind, placebo-controlled trial
Hiroyuki Hanai et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)
Epidemiological evidence for an association between habitual tea consumption and markers of chronic inflammation
Dirk De Bacquer et al.
ATHEROSCLEROSIS (2006)
Effectiveness of an 'half elemental diet' as maintenance therapy for Crohn's disease: a randomized-controlled trial
S. Takagi et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2006)
Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions
Valery N. Bochkov et al.
CIRCULATION RESEARCH (2006)
Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production
Hiroyuki Tamaki et al.
GASTROENTEROLOGY (2006)
Comparative proteomic studies on the pathogenesis of human ulcerative colitis
Sen-Yung Hsieh et al.
PROTEOMICS (2006)
Intestinal microvascular endothelium and innate immunity in inflammatory bowel disease: A second line of defense?
Jan Heidemann et al.
INFECTION AND IMMUNITY (2006)
4-hydroxynonenal modifies IgA in rat intestine after lipopolysaccharide injection
Hiroko Kimura et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-β1 and 4-hydroxynonenal in colon mucosa
Fiorella Biasi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis
Christian A. Hudert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Muc2-deficient mice spontaneously develop colitis, indicating that Muc2 is critical for colonic protection
Maria Van der Sluis et al.
GASTROENTEROLOGY (2006)
Increased etheno-DNA adducts in affected tissues of patients suffering from Crohn's disease, ulcerative colitis, and chronic pancreatitis
Jagadeesan Nair et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Maintenance infliximab does not result in increased abscess development in fistulizing Crohn's disease: results from the ACCENT II study
BE Sands et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2006)
Endothelial nitric oxide synthase in vascular disease -: From marvel to menace
U Förstermann et al.
CIRCULATION (2006)
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
RK Thimmulappa et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
S Kawanishi et al.
BIOLOGICAL CHEMISTRY (2006)
Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier
Matthew D. Neal et al.
JOURNAL OF IMMUNOLOGY (2006)
Lipoxin biosynthesis in inflammatory bowel disease
MJ Mangino et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2006)
Nutritional deficiencies in patients with Crohn's disease in remission
J Filippi et al.
INFLAMMATORY BOWEL DISEASES (2006)
The emerging role of flavonoid-rich cocoa and chocolate in cardiovascular health and disease
MB Engler et al.
NUTRITION REVIEWS (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2
E Voss et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane
Yousong Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Reduced Paneth cell α-defensins in ileal Crohn's disease
J Wehkamp et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Resolution of inflammation: The beginning programs the end
CN Serhan et al.
NATURE IMMUNOLOGY (2005)
Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines
D Porath et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Production of IL-1β, hydrogen peroxide, and nitric oxide by colonic mucosa decreases sigmoid smooth muscle contractility in ulcerative colitis
W Cao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced and emphysema
Y Ishii et al.
JOURNAL OF IMMUNOLOGY (2005)
Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells
G Leonarduzzi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Treatment of murine Th1-and Th2-mediated inflammatory bowel disease with NF-κB decoy oligonucleotides
S Fichtner-Feigl et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease
I Szanto et al.
JOURNAL OF PATHOLOGY (2005)
DSS-induced colitis is exacerbated in STAT-6 knockout mice
JW Elrod et al.
INFLAMMATORY BOWEL DISEASES (2005)
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3
RB Seth et al.
CELL (2005)
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells
S Prasad et al.
LABORATORY INVESTIGATION (2005)
Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis
M Nishikawa et al.
BRITISH JOURNAL OF CANCER (2005)
Defects in mucosal immunity leading to ulcerative colitis
SR Targan et al.
IMMUNOLOGICAL REVIEWS (2005)
Heightened responses to stressors in patients with inflammatory bowel disease
A Farhadi et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2005)
Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis
M Arita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Quantitative measurement of cytokine mRNA in inflammatory bowel disease:: relation to clinical and endoscopic activity and outcome
D Raddatz et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2005)
Radical induction theory of ulcerative colitis
Jay Pravda
WORLD JOURNAL OF GASTROENTEROLOGY (2005)
Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens
M Iimura et al.
JOURNAL OF IMMUNOLOGY (2005)
Defensin deficiency, intestinal microbes, and the clinical phenotypes of Crohn's disease
J Wehkamp et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2005)
Prohibitin: a potential target for new therapeutics
S Mishra et al.
TRENDS IN MOLECULAR MEDICINE (2005)
Activation of nuclear factor κB in colonic mucosa from patients with collagenous and ulcerative colitis
L Andresen et al.
GUT (2005)
Continuous cytokine exposure of colonic epithelial cells induces DNA damage
JB Seidelin et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2005)
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
M Kobayashi et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Protein microarray analysis of disease activity in pediatric inflammatory bowel disease demonstrates elevated serum PLGF, IL-7, TGF-β1, and IL-12p40 levels in Crohn's disease and ulcerative colitis patients in remission versus active disease
HA Kader et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2005)
Anti-TNF strategies in stenosing and fistulizing Crohn's disease
MH Holtmann et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2005)
Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-κB
K Asehnoune et al.
JOURNAL OF IMMUNOLOGY (2004)
Vi polysaccharide of Salmonella typhi targets the prohibitin family of molecules in intestinal epithelial cells and suppresses early inflammatory responses
A Sharma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle
G Kolios et al.
IMMUNOLOGY (2004)
Deficient host-bacteria interactions in inflammatory bowel disease?: The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
D Franchimont et al.
GUT (2004)
The CD40/CD40L costimulatory pathway in inflammatory bowel disease
S Danese et al.
GUT (2004)
A β-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction
S Fiorucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
β-Defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells
P Vora et al.
JOURNAL OF IMMUNOLOGY (2004)
7-Ketocholesterol enhances the expression of adhesion molecules on human aortic endothelial cells by increasing the production of reactive oxygen species
M Shimozawa et al.
REDOX REPORT (2004)
Oxidative DNA damage in the mucosa of ulcerative colitis increases with disease duration and dysplasia
R D'Inca et al.
INFLAMMATORY BOWEL DISEASES (2004)
Increased disease activity in eNOS-deficient mice in experimental colitis
M Sasaki et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms
M Bruewer et al.
JOURNAL OF IMMUNOLOGY (2003)
Inducible CD40 expression mediates NFκB activation and cytokine secretion in human colonic fibroblasts
CM Gelbmann et al.
GUT (2003)
Glutathione supplementation improves oxidative damage in experimental colitis
C Loguercio et al.
DIGESTIVE AND LIVER DISEASE (2003)
Differential mucosal expression of three superoxide dismutase isoforms in inflammatory bowel disease
L Kruidenier et al.
JOURNAL OF PATHOLOGY (2003)
Imbalanced secondary mucosal antioxidant response in inflammatory bowel disease
L Kruidenier et al.
JOURNAL OF PATHOLOGY (2003)
Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants
L Kruidenier et al.
JOURNAL OF PATHOLOGY (2003)
Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation
OA Hatoum et al.
GASTROENTEROLOGY (2003)
Intracellular IL-1 Ra type 1 inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-κB pathways
C Garat et al.
CYTOKINE (2003)
Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-α secretion from human T cells
A Ariel et al.
JOURNAL OF IMMUNOLOGY (2003)
Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease
A Keshavarzian et al.
GUT (2003)
Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium
T Kucharzik et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Cutting edge:: A novel toll/IL-1 receptor Domain containing adapter that preferentially activates the IFN-β promoter in the toll-like receptor signaling
M Yamamoto et al.
JOURNAL OF IMMUNOLOGY (2002)
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
NC Tebbutt et al.
NATURE MEDICINE (2002)
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes
L József et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Activation of PKC-β isoforms mediates HNE-induced MCP-1 release by macrophages
M Nitti et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation
M Hausmann et al.
GASTROENTEROLOGY (2002)
Lipoxin A4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis
AT Gewirtz et al.
JOURNAL OF IMMUNOLOGY (2002)
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial
SB Hanauer et al.
LANCET (2002)
α-Phenyl-N-tert-butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice
Y Naito et al.
ANTIOXIDANTS & REDOX SIGNALING (2002)
The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease
LGJ Nijtmans et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2002)
Associated changes of lipid peroxidation and transforming growth factor beta 1 levels in human colon cancer during tumour progression
F Biasi et al.
GUT (2002)
Activated platelets in ulcerative colitis enhance the production of reactive oxygen species by polymorphonuclear leukocytes
K Suzuki et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2001)
Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production
B Siegmund et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2001)
Signal transduction by tumor necrosis factor and its relatives
V Baud et al.
TRENDS IN CELL BIOLOGY (2001)
Chemiluminescence in inflammatory bowel disease patients: a parameter of inflammatory activity
B Oldenburg et al.
CLINICA CHIMICA ACTA (2001)
Mechanisms of tissue damage in inflammatory bowel disease
F Pallone et al.
CURRENT OPINION IN GASTROENTEROLOGY (2001)
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Y Ogura et al.
NATURE (2001)
Enteral feeding with a solution enriched with antioxidant vitamins A, C, and E enhances the resistance to oxidative stress
JC Preiser et al.
CRITICAL CARE MEDICINE (2000)
Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β
CK Weber et al.
GASTROENTEROLOGY (2000)
Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion
DG Binion et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
CN Serhan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins
LGJ Nijtmans et al.
EMBO JOURNAL (2000)
The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats
D Tardieu et al.
CARCINOGENESIS (2000)
Replenishment of glutathione levels improves mucosal function in experimental acute colitis
E Ardite et al.
LABORATORY INVESTIGATION (2000)
Oxidant-induced intestinal barrier disruption and its prevention by growth factors in a human colonic cell line: Role of the microtubule cytoskeleton
A Banan et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)
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